Epidemiological and clinical review on the current knowledge of EV-D68
Laboratory of Virology, Military Medical Academy, Sofia, Bulgaria, 1606 3 Geogri Sofiiski str.
Review
International Journal of Biological and Pharmaceutical Sciences Archive, 2024, 08(01), 001–005.
Article DOI: 10.53771/ijbpsa.2024.8.1.0053
Publication history:
Received on 07 May 2024; revised on 26 June 2024; accepted on 28 June 2024
Abstract:
Еnterovirus D68 (EV-D68) is a unique non-polio enterovirus, first identified in 1962. The wide spread of the virus in recent years has posed a threat to public health. EV-D68 typically causes respiratory illness, which can be mild (like a common cold) or more severe. The studies have demonstrated the potential for EV-D68 to induce neurological disease. Epidemiologic data support an association of EV-D68 with the acute flaccid myelitis (AFM)/ acute flaccid paralysis (AFP), although the mechanism remains unclear. AFM a rare, but serious neurological condition. Children are at the greatest risk of severe infection and most cases occur in children under the age of 5. EV-D68 can be detected in respiratory specimens and rarely in cerebrospinal fluid.
Keywords:
EV-D68; Respiratory tract infections; Acute flaccid myelitis; Acute flaccid paralysis
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