Fast-Melt Tablets (FMTs): Revolutionizing rapid relief-an in-depth review of swift dissolve technology
1 Department of Pharmaceutics, Maulana Azad University, Bujhawar, Jodhpur, Rajasthan, 342001, India.
2 Department of Pharmaceutics, Faculty of Pharmacy, Maulana Azad University, Bujhawar, Jodhpur, Rajasthan, 342001, India.
3 Faculty of Pharmacy, Maulana Azad University, Bujhawar, Jodhpur, Rajasthan, 342001.
4 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Maulana Azad University, Bujhawar, Jodhpur, Rajasthan, 342001, India.
Review
International Journal of Biological and Pharmaceutical Sciences Archive, 2023, 06(02), 008–036.
Article DOI: 10.53771/ijbpsa.2023.6.2.0087
Publication history:
Received on 29 August 2023; revised on 05 October 2023; accepted on 07 October 2023
Abstract:
Fast Melt tablets (FMTs) have become a promising alternative to solve a number of issues related to conventional oral dose forms. These tablets are made to quickly dissolve in the mouth and disintegrate, making them a practical and patient-friendly alternative for people who have trouble swallowing conventional solid dosage forms. This review study thoroughly examines the various uses of fast-melt tablets in the pharmaceutical business, as well as formulation strategies, production processes, and manufacturing methods. These tablets have been produced using a variety of methods, each with their own advantages and difficulties, including direct compression, freeze-drying, sublimation, and spray-drying etc. The review also talks about how excipients, disintegration agents, super disintegrants, and conventional and patented technology affect FMT performance. Fast melt tablets have found use in a variety of therapeutic fields, including pediatrics, geriatrics, and neurology, where compliance and a quick beginning of action are essential. This is in addition to their patient-friendly benefits. Additionally, their usefulness in targeted drug delivery and personalized therapy has increased because of the possibility of higher bioavailability, decreased dose frequency, and improved patient adherence. This review offers a current and thorough examination of the improvements made to fast melt tablets, covering the changes made to their production procedures, formulation methods, and effects on the pharmaceutical sector. This paper's overall goal is to be a useful resource for researchers, formulators, and pharmaceutical industry experts interested in the creation and use of fast melt tablets.
Keywords:
Fast Melt tablets (FMTs); Superdisintegrants; Patented technologies; Fast-melt Marketed product.
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0