Applications of Agrobacterium tumefaciens in the biotechnology
Laboratorio de Biotecnología Genómica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Boulevard del Maestro S/N, Esq. Elías Piña, Colonia Narciso Mendoza, CP 88710, Reynosa, Tamaulipas, México.
International Journal of Biological and Pharmaceutical Sciences Archive, 2025, 10(02), 182-185.
Article DOI: 10.53771/ijbpsa.2025.10.2.0090
Publication history:
Received 08 November 2025; revised on 12 December 2025; accepted on 16 December 2025
Abstract:
Agrobacterium tumefaciens is a ubiquitous bacterium known to cause plant diseases, particularly crown gall or tumor disease. This pathogen can drastically reduce crop yields, impacting agricultural productivity and having economic implications for producers. Diseases caused by Agrobacterium tumefaciens can disrupt local ecosystems, and its presence in infected plants creates an imbalance in flora and fauna. These diseases not only affect crops of interest but can also impact other species within the ecosystem. Managing this infection is essential to maintaining crop and ecosystem health; therefore, continuous monitoring and the promotion of management strategies to mitigate the pathogen's effects are necessary. However, Agrobacterium tumefaciens has been used as a biotechnological tool due to its ease in transferring genetic material between species, and given this property, it can introduce genes of interest that may provide an application for improving a crop, such as resistance to pests or promoting the application of gene therapy in humans or the overproduction of some metabolite of interest with beneficial agronomic and human properties.
Keywords:
Agrobacterium Tumefaciens; Galls; Crown; Pathogen; Plants; Application; Biotechnology
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Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0