Assessment of vitamin D among Sudanese Patients with Hypothyroidism

Hasna Osman Fadalla Mohamed 1, Omer Fadol Edris 2, Gad Allah Modawe 3, * and Suhair Abdelrahman Ahmed 1

1 Department of Clinical Chemistry, Faculty of Medical Laboratory Science, Al Neelain University, Khartoum, Sudan.
2 Department of Biochemistry, Faculty of Sciences and Technology, Al Neelain University, Khartoum, Sudan.
3 Department of Biochemistry, Faculty of Medicine, Omdurman Islamic University, Omdurman, Sudan.
 
Research Article
International Journal of Biological and Pharmaceutical Sciences Archive, 2021, 01(02), 057-061.
Article DOI: 10.30574/ijbpsa.2021.1.2.0024
Publication history: 
Received on 28 January 2021; revised on 01 March 2021; accepted on 04 March 2021
 
Abstract: 
Background: Vitamin D deficiency is a worldwide health issue and its role as an immune modulator has recently been emphasized. Evidence increasingly indicates the important role of vitamin D in reducing the incidence of autoimmune diseases. However, at this time the search for its role in autoimmune diseases and thyroid is not critical.
Objectives: The study aimed to assess the relationship between vitamin D deficiency in Sudanese patients with hypothyroidism.
Methods: Analytical case control hospital based study, conducted in Fadil Hospital and Police Hospital, Khartoum city, Khartoum state. The study carried out from March 2018 to September 2018. A total of 100 subjects were enrolled in the study. Vitamin D deficiency was set at levels below 20 ng / ml. Thyroid hormones (TSH, T3 and T4) were assessed in all participants using auto analyzer TOSOH AIA 313,while vitamin D was estimated using ELIZA. The data were analyzed using SPSS version (21).
Results: The study included  76(76%) females and 24(24%) males, no significance differences between thyroid profile among study population.75 (75%) deficiency of vitamin D and 25(25%) normal vitamin D. vitamin D deficiency  was significantly lower in female than male with( p =0.001).
Conclusion: The results indicated that patients with hypothyroidism suffer from vitamin D deficiency significantly associated with the degree and severity of hypothyroidism. This encourages the desirability of vitamin D supplementation and recommends the detection of vitamin D deficiency for all hypothyroidism patients.
 
Keywords: 
Vitamin D deficiency; Thyroid disease, hypothyroidism
 
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