The bioactive ingredients and therapeutic effects of Marrubium vulgare - A review
1 Dept. of Pharmacology, College of Medicine, University of Thi qar, Iraq.
2 Dept. of Pharmaceutical Chemistry, College of Pharmacy, University of Thi qar, Iraq.
3 Dept. of Biochemistry, College of Medicine, University of Thi qar, Iraq.
4 Dept. of Pharmacology and Therapeutics, Faculty of Veterinary Medicines, Damanhour University, Egypt.
5 Dept. of Microbiology School of Basic Sciences, Kazerun Branch, Islamic Azad University, Kazerun, Iran.
Review
International Journal of Biological and Pharmaceutical Sciences Archive, 2021, 01(02), 009-021.
Article DOI: 10.30574/ijbpsa.2021.1.2.0301
Publication history:
Received on 12 January 2021; revised on 01 February 2021; accepted on 03 February 2021
Abstract:
Marrubium vulgare (Family: Lamiaceae) was used traditionally in the treatment of dyspeptic complains, pulmonary infections, cough, rheumatoid arthritis, night blindness, loss of appetite, as cholagogue, purgative, diuretic, bitter tonic, carminative and appetizer. The phytochemical analysis revealed that the plant contained alkaloids, sterols, steroids, terpenoids (diterpene), saponins, flavonoid, catecholic tannins, anthocyans, phenolic compounds and many other bioactive ingredients. The pharmacological investigations showed that the plant exerted anti-inflammatory, antiedematogenic, analgesic, antioxidant, antimicrobial, antidiabetic, cardiovascular hypolipidemic, antispasmodic and many other biological effects. This review discussed the bioactive contents and pharmacological activities of Marrubium vulgare.
Keywords:
Marrubium vulgare; metabolites; constituents; traditional uses; pharmacology; therapeutic; toxicity
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