EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF PONGAMIA PINNATA FLOWERS USING ZEBRA FISH (DANIO RERIO) MODEL
Pharmacology, Malla Reddy Institute of Pharmaceutical Sciences, Maisammagudda, Telangana, India.
*Corresponding Author
ORCID Details
Pallanti Vijay Kumar: https://orcid.org/0009-0004-2523-5962
*Corresponding Author
ORCID Details
Pallanti Vijay Kumar: https://orcid.org/0009-0004-2523-5962
Research Article
International Journal of Biological and Pharmaceutical Sciences Archive, 2026, 12(02), 001–010x.
Article DOI: 10.53771/ijbpsa.2026.12.2.0098
Publication history:
Received on 02 September 2026; revised on 11 October 2026; accepted on 13 October 2026
Abstract:
Medicinal plants are widely used in traditional medicine because they contain natural compounds with therapeutic benefits and fewer side effects. Pongamia pinnata is a well-known medicinal plant reported to possess anti-inflammatory, antioxidant, and antimicrobial properties. In this study, fresh flowers of Pongamia pinnata were collected, shade dried, powdered, and extracted using ethanol. Preliminary phytochemical screening of the extract revealed the presence of important bioactive compounds such as flavonoids, alkaloids, tannins, and phenolic compounds, which may contribute to its medicinal activity. Zebrafish were selected as the experimental model due to their sensitivity, easy maintenance, and similarity to human biological systems. Inflammation was induced in the zebrafish, and different concentrations of the ethanolic flower extract were administered. The anti-inflammatory effect was evaluated by observing changes in inflammatory responses.
Keywords:
Indian beech tree (Pongamia pinnata), Zebra fish, Anti–inflammatory activity, Anesthesia Activity, Aqueous Extract.
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