Natural products targeting the p53 tumor suppressor-A novel approach for future cancer therapy- A review

Ali Esmail Al-Snafi *

Department of Pharmacology, College of Medicine, University of Thi-Qar, Iraq.
 
Review
International Journal of Biological and Pharmaceutical Sciences Archive, 2021, 01(02), 167–176.
Article DOI: 10.30574/ijbpsa.2021.1.2.0044
Publication history: 
Received on 22 April 2021; revised on 26 May 2021; accepted on 29 May 2021
 
Abstract: 
Mutations of p53, a tumor suppressor gene, are known to be involved in multiplication and metastasis of tumors. A number of natural products targeted the p53-MDM2 pathway. This review is an attempt to highlight the medicinal plants that can modulate the expression and activity ofp53tumor suppression, for cancer prevention and treatment.
 
Keywords: 
Tumor multiplication; Tumor metastasis; Natural; P53;Medicinal plants
 
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Copyright information: 
Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0