Effects of autonomic ophthalmic drugs on the visual field and colour vision of healthy Igbos
1 Department of Pharmacology and Therapeutics, ESUT College of Medicine, Parklane, GRA, Enugu, Nigeria.
2 School of Optometry, College of Medicine and Health Science, Abia State University, Uturu, Nigeria.
Research Article
International Journal of Biological and Pharmaceutical Sciences Archive, 2021, 01(02), 210–217.
Article DOI: 10.30574/ijbpsa.2021.1.2.0043
Publication history:
Received on 22 April 2021; revised on 26 May 2021; accepted on 29 May 2021
Abstract:
The study on the effects of autonomic ophthalmic drugs (miotics and mydriatics) on visual field and colour vision was conducted on visually active Igbo volunteers of either sex, whose ages ranged between 19 and 30 years and mean (19.5+0.6 years). Visual field was measured by perimetry while the colour vision testing was done using Ichihara charts and analysed on Humphrey Field Analyser (HFA).Results showed a constriction of the visual field following the administration of atropine (mydriatic) and pilocarpine (miotic) but no effect on the colour vision. Topical autonomic ophthalmic drugs have paradoxical effects on the visual field and colour vision. Phenylephrine (miotic) and timolol (mydriatic) had no effect on the visual field and colour vision, while atropine (mydriatic) and pilocarpine (miotic) constricted the visual field 32.5% and 35.4% respectively (t >0.05) without affecting the colour vision. We conclude that when autonomic ophthalmic drugs are applied according to the recommended dose and duration can cause ocular toxicity in the form of visual field changes.
Keywords:
Autonomic; Ophthalmic; Colour Vision; Visual field
Full text article in PDF:
Copyright information:
Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0