Effects of drugs on phoria status of visually active individuals (Igbos)

Samuel Agina Igwe 1, Malachy Nwaeze Ezenwaeze 1, * and Grace Ifeoma Okpalanwa 2

1 Department of Pharmacology and Therapeutics, ESUT College of Medicine, Parklane, GRA, Enugu,Nigeria.
2 School of Optometry, College of Medicine and Health Science, Abia State University,Uturu, Nigeria.
 
Research Article
International Journal of Biological and Pharmaceutical Sciences Archive, 2021, 01(02), 218–224.
Article DOI: 10.30574/ijbpsa.2021.1.2.0047
Publication history: 
Received on 22 April 2021; revised on 26 May 2021; accepted on 29 May 2021
 
Abstract: 
The effects of routinely used ophthalmic drugs were studied on the phoria status of visually active individual’si.e. Igbos on whom no data are available. These drugs include naproxen (analgesic), sulphonamide (antibiotic) and acetazolamide (diuretic). Sixty visually active individuals were selected, and von Grafe prism dissociation method was used for phoria measurements. Results showed that all the subjects were orthophoric at far and exophoric at near at the commencement of the study. It was further observed that 30% of those who received naproxen remained orthophoric at far, while at near they remained at exoposition with 12.6% reduction in total value in exophoria at the end of the study. On the other hand, all subjects treated with sulphonamide remained in exoposition at near, with 14.2% reduction in exophoria at the end of the study while at far, 50% remained in orthoposition. Furthermore, 10% of the acetazolamide treated subjects remained orthophoric at far, while at near all the subjects were in exophoric position with a reduction of 15.7% in exophoria at the end of the study. We conclude that drugs can affect the phoria status of visually active persons converting them from orthoposition to exophoria or esophoria.
 
Keywords: 
Analgesic; Antibiotic; Diuretic; Orthophoria
 
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