New unknown Sars-Cov-2 virus variants and hidden pandemics within them in developing countries

Shohreh Ghasemi 1, Zohreh Mortezania 2, Sanaz Gholami Toghchi 3 and Mahmood Dashti 4, *

1 OMFS Department of Augusta University, GA, USA.
2 Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Department of Oral and maxillofacial pathology, Dental school, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 School of Dentistry, Faculty of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
 
Review
International Journal of Biological and Pharmaceutical Sciences Archive, 2022, 03(02), 127–132.
Article DOI: 10.53771/ijbpsa.2022.3.2.0063
Publication history: 
Received on 25 April 2022; revised on 31 May 2022; accepted on 02 June 2022
 
Abstract: 
It is unclear whether the combination of one or several mutations alters the clinical and epidemiological symptoms, infectivity, pathogenicity, or vaccine efficacy of the virus. The transmission of new mutants by asymptomatic carriers is also unidentified. Antiviral drugs or vaccines have not yet been induced. Mutation pressure; however, other mutations are expected after global vaccination and after introducing verified treatments. Therefore, it is wise to be willing to bring new options to life quickly. Low-toxicity but highly genetic mutants can also be expected, which might be part of herd immunity. Clinical and rapid laboratory tests need to be developed to monitor vaccinated individuals for secondary infections caused by new variants. Significantly, personal hygiene, spatial distancing, restrictive countermeasures, facial disguises, and travel bans remain applicable fighting against the virus.
 
Keywords: 
Sequencing; Pandemic; Sars-COV2; Contamination; Developing countries
 
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