Multidisciplinary management of severe hyperemesis gravidarum complicated by cannabinoid and opioid use: A case report on the complex interplay of hyperemesis gravidarum, opioids and treatment challenges
1 Department of Pharmacy. Texas Health Alliance, Texas.
2 Department of Obstetrics & Gynecology. Texas Health Alliance, Texas.
3 Department of Pharmacology, College of Medicine, University of Thi Qar, Nasiriyah, Iraq.
Research Article
International Journal of Biological and Pharmaceutical Sciences Archive, 2024, 08(02), 001–005.
Article DOI: 10.53771/ijbpsa.2024.8.2.0073
Publication history:
Received on 14 July 2024; revised on 22 September 2024; accepted on 25 September 2024
Abstract:
Hyperemesis gravidarum (HG) presents a significant management challenge in pregnancy due to its debilitating effects on maternal health and fetal outcomes. This case report details the presentation and management of a 34-year-old primigravida at 17 weeks and 4 days gestation with severe HG. The patient’s history includes significant gastrointestinal procedures, a prior child with lissencephaly, and continued opioid use during pregnancy. Her symptoms were refractory to conventional treatments and further complicated by cannabinoid use. A multidisciplinary approach involving gastroenterology, surgery, obstetrics, pharmacists, and dietitians was employed, resulting in significant improvement. This case highlights the importance of a comprehensive care strategy in managing refractory HG complicated by substance use.
Keywords:
Hyperemesis Gravidarum; Opioids; Cannabinoids; Antiemetics; Multidisciplinary Approach.
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