Constituents and therapeutic activities of Pimpinella anisum: A review
Department of Pharmacology, College of Medicine, University of Thi-Qar, Nasiriyah, Iraq.
Review
International Journal of Biological and Pharmaceutical Sciences Archive, 2024, 08(02), 067-078.
Article DOI: 10.53771/ijbpsa.2024.8.2.0087
Publication history:
Received on 09 November 2024; revised on 21 December 2024; accepted on 23 December 2024
Abstract:
Pimpinella anisum (Apiaceae), is indigenous to Near East and widely cultivated in the temperate regions. The fruits of Pimpinella anisum were used traditionally as a spice for flavouring bread and bakery products, and the essential oil was added to foodstuff and liqueurs as a sensory and flavoring agent. It was listed as a natural source of feed flavouring by the Council of Europe. Medicinally, the fruits were used as expectorant, digestive, antispasmodic, carminative, parasiticide, for bronchial catarrh, pertussis, spasmodic cough, spasmodic gastrointestinal complaints, to increase milk secretion, to promote menstruation, to facilitate birth, to alleviate symptoms of the male climacteric, to increase libido and externally for pediculosis and scabies. The recent studies showed that Pimpinella anisum possessed Antioxidant, hepatoprotective, nephroprotective, antihypertensive, hypolipidemic, Antiinflammatory, antimicrobial, antiparasitic, antidiabetic, local anesthetic, anticonvulsant, hypnotic, antidepressant, anxiolytic, anti-cholinesterase, neuroprotective, immunomodulatory, anticancer, laxative effects and increased milk production, prevented osteoporosis and minimized premenstrual syndrome. The current review was designed to highlight the chemical constituents and pharmacological effects of Pimpinella anisum.
Keywords:
Pimpinella anisum; Anise; Constituents; Pharmacology; Toxicology
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