Simulation of potential action of stimulated external alternating current (AC) in nerve cells using Hindmarsh-Rose model

Siti Aisah Sekar Arum 1, *, Yuyun Yueniwati 2 and Mauludi Ariesto Pamungkas 3

1 Department of Physics, Faculty of Mathematics and Natural Sciences, Brawijaya University, Jl. Veteran, Malang, 65143, Indonesia.
2 Department of Radiology, Faculty of Medicine, Brawijaya University, Jl. Veteran, Malang, 65143, Indonesia.
3 Department of Physics, Faculty of Mathematics and Natural Sciences, Brawijaya University, Jl. Veteran, Malang, 65143, Indonesia.
 
Research Article
International Journal of Biological and Pharmaceutical Sciences Archive, 2021, 01(01), 016-022.
Article DOI: 10.30574/ijbpsa.2021.1.1.0004
Publication history: 
Received on 03 January 2021; revised on 10 January 2021; accepted on 12 January 2021
 
Abstract: 
This paper describes the simulation of potential actions that occur in nerve cells when given frequency variation as a stimulus. The simulation aims to determine the response of nerve cells to various combinations of currents in this case frequency. The simulation results showed that oscillations occur when the given frequency is 0.045 Hz. While the neural cell response occurs when the frequency between 0.055 Hz-0.065 Hz. The method carried out by the author is to modify the model of Hindmarsh-Rose nerve cells and then simulate it using Matlab programming language. Based on the research that has been done it can be concluded that at a frequency of 0.055 Hz a potential signal of action is formed and oscillates. In the human body, nerve cells and muscle cells are cells that have the ability of excitability (stimulated) because it has membrane potential. Short fluctuations of such cells, serve as electrical signals.
 
Keywords: 
Potential action; Periodic current; Hindmarsh-Rose model
 
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