Chemical constituents and pharmacological activities of Mirabilis jalapa- A review
1Dept. of Pharmacology, College of Medicine, University of Thi qar, Iraq.
2 Dept. of Biochemistry, College of Medicine, University of Thi qar, Iraq.
3 Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia.
Review
International Journal of Biological and Pharmaceutical Sciences Archive, 2021, 01(02), 034-045.
Article DOI: 10.30574/ijbpsa.2021.1.2.0303
Publication history:
Received on 13 January 2021; revised on 01 February 2021; accepted on 03 February 2021
Abstract:
Mirabilis jalapa was used traditionally in the treatment of kidney infections, as diuretic, tonic, cathartic, purgative and emetic. The phytochemical screening of the extracts of the leaves and stems of the Mirabilis jalaparevealed the presence of tannins, alkaloids, flavonoids, phenolic compounds, carbohydrates, terpenes, glycosides, saponins, protein, cardiac glycosides, steroids and emodin. The previous pharmacological studies revealed that Mirabilis jalapa possessed wide range of pharmacological and therapeutic effects included antimicrobial, antiparasitic, dermatological, anticancer, anti-inflammatory, analgesic, antidiabetic, antihistaminic, immune-modulatory, antispasmodic and many other pharmacological effects. The chemical constituents, nutritional, pharmacological and therapeutic effects ofMirabilis jalapawere discussed in the current review.
Keywords:
Mirabilis jalapa; constituents; traditional uses; pharmacology; therapeutic; toxicology
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